Ipamorelin

Ipamorelin is a growth hormone-releasing peptide that stimulates natural GH without affecting cortisol or prolactin levels. It’s used for recovery, anti-aging, and fat loss.

Its a mild, well-tolerated peptide ideal for daily use.

Key Clinical Benefits:

• Stimulates natural growth hormone release
• Improves body composition
• Promotes fat burning
• Enhances muscle recovery
• Improves sleep and mood
  

Literature on ipamorelin: Raun K, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. This is the foundational paper describing ipamorelin’s pharmacology and selectivity.

PubMed:
https://pubmed.ncbi.nlm.nih.gov/9849822/

Gobburu JV, et al. (1999). Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Early Phase I study evaluating pharmacokinetics and growth hormone response in healthy volunteers.

PubMed:
https://pubmed.ncbi.nlm.nih.gov/10496658/

Agersø H, et al. (1998). Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption. Examines absorption, metabolism, and pharmacokinetics in animal models.

PubMed:
https://pubmed.ncbi.nlm.nih.gov/9879640/

Beck DE, et al. (2014). Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Phase II randomized, placebo-controlled clinical trial.

PubMed:
https://pubmed.ncbi.nlm.nih.gov/25331030/